Oral Vitamin B12 Therapy after Total Gastrectomy

Pancreatic function and the absorption of fat, iron, vitamin B12, and calcium after total gastrectomy

In the surgical treatment of gastric cancer total gastrectomy may be required. Such an extensive surgical procedure is only justified if the operative mortality is sufficiently low and the patient's general condition after the operation tolerable. The first patient who survived total gastrectomy was operated upon by Schlatter in 1897. A few months later Hofmann (1898) demonstrated that the pati...

Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency.

BACKGROUND Vitamin B12 deficiency is common, and the incidence increases with age. Most people with vitamin B12 deficiency are treated in primary care with intramuscular (IM) vitamin B12. Doctors may not be prescribing oral vitamin B12 formulations because they may be unaware of this option or have concerns regarding its effectiveness. OBJECTIVES To assess the effects of oral vitamin B12 vers...

Pancreatic function and the absorption of fat, iron, vitamin B12, and calcium after total gastrectomy for gastric cancer.

Oral manifestations in vitamin B12 deficiency patients with or without history of gastrectomy

BACKGROUND The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy. METHODS Twenty-two patients with vitamin B12 deficiency were included. Patients' chief complaints, oral manifestations, blood examination results, and past medical histories were reviewed. RESULTS Eleven patients ha...

Hyperhomocysteinaemia, folate and vitamin B12 in unsupplemented haemodialysis patients: effect of oral therapy with folic acid and vitamin B12.

BACKGROUND Hyperhomocysteinaemia, a risk factor for atherosclerosis, is common in dialysis patients and particularly in those homozygous for a common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene (C677T transition). B-complex vitamin supplements have been shown to lower plasma total homocysteine (tHcy) concentrations, but the respective effectiveness of folate and or...